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Puberteit en puberteitsstoornissen: biologische regulatie, psychologische ontwikkeling en behandeling

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Tijdschrift voor kindergeneeskunde

Abstract

Puberty is a very important phase of development in adolescents. Physical as well as psychosocial changes prepare them for the adult role. With respect to the endocrine aspects, puberty appears to be a phase in a continuum of brain development starting during the fetal period. In the last decades, puberty seems to start earlier, although progression of puberty is slower. Pubertal disorders not only may have their consequences on psychosocial development, but also on final height. Central precocious puberty, mostly seen in girls, has a more progressive pattern than physiologic puberty; it may result in impaired final height and problems of the child with age-matched peers. Delayed puberty and hypogonadotropic hypogonadism may induce isolation and negative self-esteem of the teenager.

This paper focuses on the physiologic regulation of pubertal development, endocrine as well as psychosocial aspects. In addition, underlying mechanisms, consequences and possible interventions in case of pubertal disorders are discussed.

Samenvatting

De puberteit is een ingrijpende ontwikkelingsfase op de weg naar volwassenheid, zowel in lichamelijk opzicht als wat betreft de psychologische problematiek. Endocrinologisch gezien is de puberteit de laatste fase van een centrale ontwikkeling die startte in de foetale periode. In de afgelopen decennia is er een trend van steeds vroeger optreden van de eerste ontwikkeling van de geslachtskenmerken. De progressie van de puberteit is echter langzamer, zodat de menarcheleeftijd niet vroeger valt. Stoornissen wat betreft de timing van de puberteit kunnen leiden tot psychosociale problemen. Kinderen met pubertas praecox zijn aanvankelijk lang ten opzichte van leeftijdgenoten, maar uiteindelijk zijn ze vaak aan de kleine kant; daarnaast ontstaan door de puberteitskenmerken vaak relationele problemen. Verlate puberteit kan leiden tot stress in die zin, dat de adolescent (dit geldt vooral voor jongens) zich isoleert van leeftijdgenoten. Dit artikel gaat in op de fysiologie van de puberteit, zowel wat betreft hormonale regulatie als wat betreft psychosociale aspecten. Verder worden de oorzaken, gevolgen en mogelijke interventies bij puberteitsstoornissen besproken.

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Literatuur

  • Roede MJ, Wieringen JC van. Growth diagrams 1980. Tijdschrift voor Sociale Gezondheidszorg 1985;63 (suppl):1-34.

    Google Scholar 

  • Metcalf MG, Skidmore DS, Lowry GF, Mackenzie JA. Incidence of ovulation in the years after menarche. J Endocrinol 1983;97:213-9.

    Article  CAS  PubMed  Google Scholar 

  • Fredriks AM, Buuren S van, Burgmeijer RJ, et al. Continuing positive secular growth change in The Netherlands 1955-1997. Pediatr Res 2000;47:316-23.

    Article  CAS  PubMed  Google Scholar 

  • Mul D. Treatment of early puberty in adopted and non-adopted children: when, why and how? Proefschrift, Erasmus Universiteit Rotterdam, 2000.

    Google Scholar 

  • Herman-Giddens ME, Slora EJ, Wasserman RC, et al. Secondary sexual characteristics and menses in young girls seen in office practice: a study from pediatric research in office settings network. Pediatrics 1997;505-12.

  • Kaplowitz PB, Oberfield SE. Reexamination of the age limit for defining when puberty Is precocious in girls in the United States: implications for evaluation and treatment. Pediatrics 1999;104:936-41.

    Article  CAS  PubMed  Google Scholar 

  • Gendrel DG, Chaussain JL, Roger M, Job JC, Simultaneous postnatal rise of plasma lh and testosterone in male infants. J Pediatr 1980;97:600-2.

    Article  CAS  PubMed  Google Scholar 

  • Winter JSD, Daiman C, Hobson WC, et al. Pituitary-gonadal relations in infancy! Pattern of serum gonadotropin concentrations from birth to four years of age in man and chimpanzee. J Clin Endocrinol Metab 1975;40:545-51.

    Article  CAS  PubMed  Google Scholar 

  • Wennink JMB. Pulsatile hormone patterns in human puberty. Proefschrift. Vrije Universiteit Amsterdam,1990.

    Google Scholar 

  • Grumbach MM, Styne DM. Behavioral changes of puberty. In: Wilson: Willems Textbook of Endocrinology, 9e druk. Philadelphia, Saunders Company, 1998:1524-6.

    Google Scholar 

  • Wit J de, Veer G van der, Slot NW. Psychologie van de adolescentie. Baarn: Uitgeverij Intro, (20e druk), 1995.

    Google Scholar 

  • Paikoff, RL, Brooks-Gunn J, Warren MP. Effects of girls' hormonal status on depressive and aggressive symptoms over the course of one year. J Youth Adolesc 1991;20 [2]:191-215.

    Article  Google Scholar 

  • Meschke LL, Silbereisen RK. The influence of puberty, family processes, and leisure activities on the timing of first sexual experience. J Adolesc, 1997;20:403-18.

    Article  CAS  PubMed  Google Scholar 

  • Collins WA. Research on the transition to adolescnce: continuity in the study of developmental processes. In: Gunnar MR, Collins WA (eds). Minnesota symposium on child development,vol 21. Hilldale NJ: Erlbaum, 1988:1-15.

    Google Scholar 

  • Susman EJ, Finkelstein JW, Chinchilli VM, et al. The effect of sex hormone replacement therapy on behavior problems and moods in adolescents with delayed puberty. J Pediatr 1998;133[4]:521-5.

    Article  CAS  PubMed  Google Scholar 

  • Piaget J. Zes psychologische studies. Deventer: Van Loghum Slaterus, 1969.

    Google Scholar 

  • Erikson EH. Identiteit, jeugd en crisis. Utrecht/Antwerpen: Uitgeverij het Spectrum, 1971.

    Google Scholar 

  • Eichorn DH. Biological correlates of behavior. In: Stevenson HW (ed). Child psychology: Yearbook of the national society for the study of educations. 1963;62:4-61.

  • Peskin H. Pubertal onset and ego functioning. J Abnorm Psychol 1967;72 [1]:1-15.

    Article  CAS  PubMed  Google Scholar 

  • Apter A, Galatzer A, Beth Halachmi N, Laron Z. Self image in adolescents with delayed puberty and growth retardation. J Youth Adolesc 1981;10 [6]:501-5.

    Article  Google Scholar 

  • Susman EJ, Nottelman ED, Inoff-Germain GE, et al. The relation of relative hormonal levels and physical development and social-emotional behavior in young adolescens. J Youth Adolesc 1985;14 [3]:245-64.

    Article  Google Scholar 

  • Duncan PD, Ritter PL, Dornbusch SM, et al. The effects of pubertal timing on body image, school behavoir, and deviance. J Youth Adolesc 1985;14 [3]:227-35.

    Article  Google Scholar 

  • Blyth DA, Simmons RG, Zakin DF. Satisfaction with body image for early adolescent females: the impact of pubertal timing within different school environments. J Youth Adolesc 1985;14 [3]:207-25.

    Article  Google Scholar 

  • Magnussen D, Stattin H, Allen VL. Biological maturation and social development: A longitudinal study of some adjustment processes from mid-adolescent to adulthood. J Youth Adolesc 1985;14 [4]:267-83.

    Article  Google Scholar 

  • Peterson AC, Crockett L. Pubertal timing and grade effects on adjustment. J Youth Adolesc 1985;14 [3]:191-206.

    Article  Google Scholar 

  • Aro H, Taipale V. The impact of timing of puberty on psychosomatic symptoms among fourteen- to sixteen-year-old Finnish girls. Child Devel 1987;58:261-8.

    Article  CAS  Google Scholar 

  • Nottelman ED, Susman EJ, Inoff-Germain G, et al. Developmental processes in early adolescence: relationships between adolescent adjustment problems and chronologic age, pubertal stage, and puberty-related serum hormone levels. J Pediatr 1987;473-80.

  • Graber JA, Lewinsohn PM, Seeley JR, Brooks-Gunn J. Is psychopathology associated with the timing of pubertal development. J Am Acad Child Adolesc Psychiatr 1997;36 [12]:1768-76.

    Article  CAS  Google Scholar 

  • Schroor EJ, Van Weissenbruch MM, Delemarre-Van de Waal HA. Long term GnRH-agonist treatment does not postpone central development of the GnRH pulse generator in girls with idiopathic precocious puberty. J Clin Endocrinol Metab 1995;80:1696-701.

    Article  CAS  PubMed  Google Scholar 

  • Oostdijk W, Partch CJ, Drop SLS, Sippell WG. Hormonal evaluation during and after long-term treatment with a slow-release GnRH-agonist of children with central precocious puberty; effect on final height. In: The neurobiology of puberty. Bristol: J of Endocrinology Ltd 1995;319-25.

  • Higham E. Variations in adolescent psychohormonal development. In: Adelson J (ed). Handbook of adolescent psychology. New York: Wiley & 38; Sons,1980;472-94.

    Google Scholar 

  • Sonis WA, Comite F, Blue J, et al. Behavior problems and social competence in girls with true precocious puberty. J Pediatr 1985;106:156-60.

    Article  CAS  PubMed  Google Scholar 

  • Rierdan J, Koff E. Depressive symptomatology among very early maturing girls. J Youth Adolesc 1991;20 [4]:415-25.

    Article  Google Scholar 

  • Ehrhardt AA, Meyer-Bahlberg HFL, Bell JJ. Idopathic precocious puberty in girls: psychiatric follow-up in adolescence. J Am Acad Child Psychiatr 1984;23:23-33.

    CAS  Google Scholar 

  • Meyer-Bahlburg HFL, Ehrhardt AA, Bell JJ, et al. Idiopathic precocious puberty in girls: psychosexual development. J Youth Adolesc 1985;14 [4]:339-53.

    Article  Google Scholar 

  • Xhrouet-Heinrichs D, Lagrou K, Heinrichs C, et al. Longitudinal study of behavioural and affective patterns in girls with central precocious puberty during long-acting triptorelin therapy. Acta Paediatr 1997;86 [8]:808-15.

    Article  CAS  PubMed  Google Scholar 

  • Schroor EJ, Van Weissenbruch MM, Knibbe P, Delemarre-Van de Waal HA. The effect of prolonged administration of an anabolic steroid (oxandrolone) on growth in boys with constitutionally delayed growth and puberty. Eur J Pediatr 1995;154:953-7.

    Article  CAS  PubMed  Google Scholar 

  • Huisman J, Bosch JD, Delemarre-Van de Waal HA. Personality development of adolescents with hypogonadotropic hypogonadism. Psychological Reports 1996;79:1123-6.

    CAS  PubMed  Google Scholar 

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H.A. Delemarre-van de Waal, afdeling Kindergeneeskunde en J. Huisman, afdeling Medische psychologie, vu medisch centrum, Postbus 7057, 1007 MB Amsterdam.

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Delemarre-van de Waal, H.A., Huisman, J. Puberteit en puberteitsstoornissen: biologische regulatie, psychologische ontwikkeling en behandeling. KIND 69, 145–151 (2001). https://doi.org/10.1007/BF03061347

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