Synthesis of naturally occurring partial methyl ethers of myricetin
- Cite this article as:
- Sarma, P.N., Srimannarayana, G. & Subba Rao, N.V. Proc. Indian Acad. Sci. (1974) 80: 168. doi:10.1007/BF03046674
The synthesis of combretol, annulatin, and europetin—naturally occurring partial methyl ethers of myricetin—is described. Condensation of 2, 4, 6-trihydroxy-ω-methoxyacetophenone with tri-O-methyl galloyl chloride or tri-O-benzyl galloyl chloride furnished the appropriate 3-methoxyflavones, which by a series of reactions furnished the natural myricetin derivatives.