Proceedings of the Indian Academy of Sciences - Section A

, Volume 80, Issue 4, pp 168–173

Synthesis of naturally occurring partial methyl ethers of myricetin


  • P. N. Sarma
    • Department of ChemistryOsmania University
  • G. Srimannarayana
    • Department of ChemistryOsmania University
  • N. V. Subba Rao
    • Department of ChemistryOsmania University

DOI: 10.1007/BF03046674

Cite this article as:
Sarma, P.N., Srimannarayana, G. & Subba Rao, N.V. Proc. Indian Acad. Sci. (1974) 80: 168. doi:10.1007/BF03046674


The synthesis of combretol, annulatin, and europetin—naturally occurring partial methyl ethers of myricetin—is described. Condensation of 2, 4, 6-trihydroxy-ω-methoxyacetophenone with tri-O-methyl galloyl chloride or tri-O-benzyl galloyl chloride furnished the appropriate 3-methoxyflavones, which by a series of reactions furnished the natural myricetin derivatives.

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© Indian Academy of Sciences 1974