Medizinische Klinik

, Volume 92, Supplement 3, pp 3–4

Selensubstitution bei Sepsispatienten

Eine prospektiv randomisierte Studie
  • Thomas Zimmermann
  • Steffen Albrecht
  • Helmut Hühne
  • Ullrich Vogeslang
  • Robert Grützmann
  • Steffi Kopprasch
Article

DOI: 10.1007/BF03041947

Cite this article as:
Zimmermann, T., Albrecht, S., Hühne, H. et al. Med Klin (1997) 92(Suppl 3): 3. doi:10.1007/BF03041947

Substitution of selenium in septic patients

A prospective randomized study

Summary

Patients and Method: In this study the effect of antioxidative therapy with sodium selenite was investigated in patients with systemic inflammatory response syndrome (S. I. R. S.) and multiple organ failure. 40 patients were included in this prospective randomized study. The patients were observed over a period of 28 days. The letality rate within 28 days was excepted as main criteria. The Apache-II and the MOF-Score of Goris were used as clinical parameters. 20 patients were treated with sodium selenite ver a period of 28 days.

Result: This antioxidative therapy reduced the letality rate from 40 to 15%.

Key Words

Septicemia Systemic inflammatory response syndrome Multiple organ failure Substitution of selenium 

Copyright information

© Urban & Vogel 1997

Authors and Affiliations

  • Thomas Zimmermann
    • 1
  • Steffen Albrecht
    • 2
  • Helmut Hühne
    • 3
  • Ullrich Vogeslang
    • 4
  • Robert Grützmann
    • 1
  • Steffi Kopprasch
    • 2
  1. 1.Klinik für Viszeral-, Thorax- und Gefäßchirurgie der TU DresdenDresden
  2. 2.Klinik für Gynäkologie und GeburtshilfeGermany
  3. 3.Abteilung für Pathobiochemie der III. Medizinischen Klinik des Universitätsklinikums „Carl Gustav Carus“ der TU DresdenGermany
  4. 4.Chirurgische AbteilungKrankenhaus MeißenGermany

Personalised recommendations