Biological Trace Element Research

, 42:63

The antioxidant enzymes activity in the conditions of systemic hypersilicemia

Authors

  • Jacek Najda
    • Department of Internal DiseasesSilesian Medical Academy
  • Malgorzata Goss
    • Department of Internal DiseasesSilesian Medical Academy
  • Jan Gmínski
    • Department of Internal DiseasesSilesian Medical Academy
  • Ludmiła Weglarz
    • Department of Internal DiseasesSilesian Medical Academy
  • Krzysztof Siemianowicz
    • Department of Internal DiseasesSilesian Medical Academy
  • Zofia Olszowy
    • Department of Internal DiseasesSilesian Medical Academy
Article

DOI: 10.1007/BF02990489

Cite this article as:
Najda, J., Goss, M., Gmínski, J. et al. Biol Trace Elem Res (1994) 42: 63. doi:10.1007/BF02990489

Abstract

The effect of an excessive inorganic silicon oral intake on the activity of basic antioxidant enzymes was studied in rats. Activities of superoxide dismutase, catalase, and glutathione peroxidase were measured in liver and kidney tissues of animals receiving per os sodium metasilicate nonahydrate (Na2SiO3.9H2O) (Sigma, [St. Louis, MO]) dissolved in their drinking water. A decrease of the activity of all the studied enzymes was found in the samples derived from the experimental group. The results obtained indicate the free oxygen radicals participation in the potential pathologic events in the conditions of systemic hypersilicemia.

Index Entries

Siliconsuperoxide dismutase (SOD)catalase (CAT)glutathione peroxidase (GSH-Px)
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Copyright information

© Humana Press Inc. 1994