Regulation of Hematopoiesis by Chemokine Family Members
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- Broxmeyer, H.E. Int J Hematol (2001) 74: 9. doi:10.1007/BF02982544
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Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells.