Review Article

Breast Cancer

, Volume 11, Issue 4, pp 343-349

First online:

Pathological approach to evolving prognostic and predictive factors of breast cancer

  • Koji ArihiroAffiliated withDepartment of Anatomical Pathology, Hiroshima University Hospital Email author 

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Abstract

Among the evolving concepts of prognostic and predictive factors in breast carcinoma pathology are those relating to lymph node status, tumor size, histological type, histological grade, bone marrow micrometastasis, and lymphatic and blood vessel involvement. Correct identification based on a uniform and complete pathological evaluation of tumor specimens is vital to correctly decide treatment. In addition we describe inflammatory cell infiltrates in breast carcinoma as not only prognostic and predictive factors but also pleiotropic regulators and/or effectors.

Key words

Breast cancer Prognosis Predictive factors Inflammatory cells