Breast Cancer

, Volume 7, Issue 1, pp 99–103

Comparative efficacy of positron emission tomography and ultrasonography in preoperative evaluation of axillary lymph node metastases in breast cancer

  • Masatoshi Ohta
  • Yutaka Tokuda
  • Yuki Saitoh
  • Yasuhiro Suzuki
  • Akira Okumura
  • Mitsuhiro Kubota
  • Hiroyasu Makuuchi
  • Tomoo Tajima
  • Seiei Yasuda
  • Akira Shohtsu
Original Article

DOI: 10.1007/BF02967197

Cite this article as:
Ohta, M., Tokuda, Y., Saitoh, Y. et al. Breast Cancer (2000) 7: 99. doi:10.1007/BF02967197

Abstract

Purpose

In primary breast cancer, axillary nodal status is the most powerful predictive factor of recurrence. However, axillary lymph node dissection may cause surgical complications. If preoperative evaluation of axillary lymph node metastases is possible, unnecessary axillary lymph node dissections can be avoided. The purpose of this study was to evaluate the efficacy of positron emission tomography (PET) on detection of axillary lymph node metastases in breast cancer.

Methods

PET scans of the axilla were obtained in 32 patients with primary breast cancer. All patients fasted for at least 4 hours before the examination. After transmission scans for attenuation correction were performed, emission scans after intravenous injection of 2-[18F]-fluoro-2-deoxy-D-glucose (FDG) were obtained.

Results

Overall accuracy of PET alone, ultrasonography alone, and in combination in the detection of axillary metastases were 82%, 79%, and 85% respectively.

Conclusion

There were no significant differences between PET, ultrasonography, and PET in combination with ultrasonography regarding sensitivity, specificity and accuracy in the detection of axillary metastases.

Key words

Breast cancerPETAxillary lymph node metastases

Abbreviations

PET

Positron emission tomography

FDG

2-[l8F]-fluoro-2-deoxy-D-glucose

Copyright information

© The Japanese Breast Cancer Society 2000

Authors and Affiliations

  • Masatoshi Ohta
    • 1
  • Yutaka Tokuda
    • 1
  • Yuki Saitoh
    • 1
  • Yasuhiro Suzuki
    • 1
  • Akira Okumura
    • 1
  • Mitsuhiro Kubota
    • 1
  • Hiroyasu Makuuchi
    • 1
  • Tomoo Tajima
    • 1
  • Seiei Yasuda
    • 2
  • Akira Shohtsu
    • 2
  1. 1.Department of SurgeryTokai University School of MedicineJapan
  2. 2.Himedic Imaging Center at Lake YamanakakoJapan
  3. 3.Department of SurgeryTokai University School of MedicineIseharaJapan