Breast Cancer

, Volume 7, Issue 4, pp 341–344

Treatment of noninvasive carcinoma: Fifteen-Year results at the National Cancer Center Hospital in Tokyo

  • Sadako Akashi-Tanaka
  • Takashi Fukutomi
  • Takeshi Nanasawa
  • Kaneyuki Matsuo
  • Tadashi Hasegawa
  • Hitoshi Tsuda
Panel Discussion II

DOI: 10.1007/BF02966402

Cite this article as:
Akashi-Tanaka, S., Fukutomi, T., Nanasawa, T. et al. Breast Cancer (2000) 7: 341. doi:10.1007/BF02966402

Abstract

The introduction of screening mammography (MMG) will lead to increased detection of preclinical early breast cancer in Japan. It has become more important to understand the nature of these lesions. We tried to elucidate the long term prognosis and clinical and pathological characteristics of noninvasive cancers.

A total of 336 (5.4%) ductal carcinomain situ (DCIS) and 32 (0.5%) lobular carcinomain situ (LCIS) were diagnosed in 6 277 breast carcinomas at the National Cancer Center Hospital from 1962 to 1995. Most (80%) LCIS occurred in premenopausal women. LCIS has significantly higher bilaterality than that of DCIS. Local recurrence occurred in approximately 10% of patients after breast conserving surgery for DCIS and LCIS. Four patients died of breast carcinoma, which were initially diagnosed as noninfiltrating carcinoma. The 15-year cause specific survival rates of patients with DCIS and LCIS were 98.5 % and 100 %, respectively.

Key words

Breast cancerDuctal carcinomain situLobular carcinomain situLong term result

Abbreviations

MMG

Mammography

DCIS

Ductal carcinomain situ

LCIS

Lobular carcinomain situ

Copyright information

© The Japanese Breast Cancer Society 2000

Authors and Affiliations

  • Sadako Akashi-Tanaka
    • 1
  • Takashi Fukutomi
    • 1
  • Takeshi Nanasawa
    • 1
  • Kaneyuki Matsuo
    • 1
  • Tadashi Hasegawa
    • 2
  • Hitoshi Tsuda
    • 2
  1. 1.Division of Breast SurgeryNational Cancer Center HospitalJapan
  2. 2.Pathology DivisionNational Cancer Center Research InstituteJapan
  3. 3.Division of Breast SurgeryNational Cancer Center HospitalTokyoJapan