Current Hepatitis Reports

, Volume 6, Issue 1, pp 9–16

Serum hepatitis B virus DNA as a predictor of the development of cirrhosis and hepatocellular carcinoma


    • Genomics Research CenterAcademia Sinica
  • Uchenna H. Iloeje
    • Genomics Research CenterAcademia Sinica
  • Hwai-I Yang
    • Genomics Research CenterAcademia Sinica

DOI: 10.1007/BF02942173

Cite this article as:
Chen, C., Iloeje, U.H. & Yang, H. Current Hepatitis Reports (2007) 6: 9. doi:10.1007/BF02942173


Chronic hepatitis B frequently progresses to cirrhosis and hepatocellular carcinoma. An elevated serum level of hepatitis B virus DNA is a major risk factor for cirrhosis and hepatocellular carcinoma, and there is a dose-response relationship between the serum hepatitis B virus DNA level and the risk of these complications. To lower the viral load to its lowest level is the method of choice to prevent major liver complications in chronic hepatitis B.

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© Current Medicine Group LLC 2007