The Japanese Journal of Thoracic and Cardiovascular Surgery

, Volume 49, Issue 2, pp 141–144

Surgical management of multidrug-resistant tuberculosis

Authors

  • Susumu Sasano
    • Department of Surgery ITokyo Women's Medical University
  • Hiroshi Yamamoto
    • Department of Chest SurgeryTokyo Metropolitan Fuchu Hospital
  • Tokuro Otsuka
    • Department of Chest SurgeryTokyo Metropolitan Fuchu Hospital
  • Akria Fujita
    • Respiratory MedicineTokyo Metropolitan Fuchu Hospital
  • Takamasa Onuki
    • Department of Surgery ITokyo Women's Medical University
  • Sumio Nitta
    • Department of Surgery ITokyo Women's Medical University
Article

DOI: 10.1007/BF02912135

Cite this article as:
Sasano, S., Yamamoto, H., Otsuka, T. et al. Jpn J Thorac Cardiovasc Surg (2001) 49: 141. doi:10.1007/BF02912135

Abstract

We report surgical resections in 3 patients with active multidrug-resistant tuberculosis. All cases involved strains of Mycobacterium tuberculosis resistant to at least isoniazid and rifampin and patients who were poor candidates for medical therapy alone. We conducted pulmonary resections (partial resection in case I, lobectomy in case 2, and segmentectomy in case 3). The optimum multiple-drug regimen, based on drug susceptibility studies, was used preoperatively and postoperatively. In all cases, sputum smears and cultures yielded negative results postoperatively, and continue to be negative for Mycobacterium tuberculosis to date. It is recomended that, if localized disease is present and medical treatment is likely to fail, pulmonary resection be conducted for multidrug-resistant Mycobacterium tuberculosis.

Key words

pulmonary tuberculosismultidrug-resistant tuberculosispulmonary resectionsurgery
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Copyright information

© Japanese Association for Thoracic Surgery 2001