The Japanese Journal of Thoracic and Cardiovascular Surgery

, Volume 49, Issue 2, pp 141–144

Surgical management of multidrug-resistant tuberculosis

  • Susumu Sasano
  • Hiroshi Yamamoto
  • Tokuro Otsuka
  • Akria Fujita
  • Takamasa Onuki
  • Sumio Nitta
Article

DOI: 10.1007/BF02912135

Cite this article as:
Sasano, S., Yamamoto, H., Otsuka, T. et al. Jpn J Thorac Cardiovasc Surg (2001) 49: 141. doi:10.1007/BF02912135
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Abstract

We report surgical resections in 3 patients with active multidrug-resistant tuberculosis. All cases involved strains of Mycobacterium tuberculosis resistant to at least isoniazid and rifampin and patients who were poor candidates for medical therapy alone. We conducted pulmonary resections (partial resection in case I, lobectomy in case 2, and segmentectomy in case 3). The optimum multiple-drug regimen, based on drug susceptibility studies, was used preoperatively and postoperatively. In all cases, sputum smears and cultures yielded negative results postoperatively, and continue to be negative for Mycobacterium tuberculosis to date. It is recomended that, if localized disease is present and medical treatment is likely to fail, pulmonary resection be conducted for multidrug-resistant Mycobacterium tuberculosis.

Key words

pulmonary tuberculosismultidrug-resistant tuberculosispulmonary resectionsurgery

Copyright information

© Japanese Association for Thoracic Surgery 2001

Authors and Affiliations

  • Susumu Sasano
    • 3
  • Hiroshi Yamamoto
    • 1
  • Tokuro Otsuka
    • 1
  • Akria Fujita
    • 2
  • Takamasa Onuki
    • 3
  • Sumio Nitta
    • 3
  1. 1.Department of Chest SurgeryTokyo Metropolitan Fuchu HospitalTokyoJapan
  2. 2.Respiratory MedicineTokyo Metropolitan Fuchu HospitalTokyoJapan
  3. 3.Department of Surgery ITokyo Women's Medical UniversityTokyoJapan