Pathology & Oncology Research

, Volume 3, Issue 3, pp 215–218

Giant cell hepatitis in adults

  • Gábor Lotz 
  • Pál Koltai 
  • Zsuzsa Schaff 
case report

DOI: 10.1007/BF02899924

Cite this article as:
Gábor, L., Pál, K. & Zsuzsa, S. Pathol. Oncol. Res. (1997) 3: 215. doi:10.1007/BF02899924

Abstract

Giant cell hepatitis is a frequent reaction of the liver to different injuries in newborns and in childhood, but rare in adults. This form of hepatitis is often accompanied by cholestasis and shows fast progression to cirrhosis. In most cases autoimmune, metabolic, toxic or viral origin can be found, but sometimes the etiology remains hidden. This paper introduces two adult giant cell hepatitis cases. Hepatitis C virus infection was the possible origin in the first case and autoimmune disease in the other one.

Key words

giant cell hepatitis adult 

Abbreviations

ALAT

alanine aminotransferase

ALP

alkaline phosphatase

ANA

antinuclear antibody

AMA

antimitochondrial antibody

ASAT

aspartate aminotransferase

ELISA

enzymelinked immunosorbent assay

GCH

giant cell hepatitis

GGT

gamma-glutamyl transpeptidase

GHC

giant hepatocyte(s)

HBsAg

Hepatitis B virus surface antigen

HCs

hepatocytes

HCV

hepatitis C virus

HLA

Human Leukocyte Antigen

IgG

immunoglobulin

LSP

liver specific lipoprotein

MU

million unit

PIGCH

post-infantile giant cell hepatitis

Se Bi

serum bilirubin level

SGCH

syncytial giant cell hepatitis

SMA

anti-smooth muscle antibody

WBC

white blood cells

Copyright information

© Arányi Lajos Foundation 1997

Authors and Affiliations

  • Gábor Lotz 
    • 1
  • Pál Koltai 
    • 1
  • Zsuzsa Schaff 
    • 1
  1. 1.1st Institute of Pathology and Experimental Cancer ResearchSemmelweis University of MedicineBudapest

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