Advances in Therapy

, Volume 24, Issue 6, pp 1202–1209

Ultra-low microcurrent therapy: A novel approach for treatment of chronic resistant wounds


  • Bok Y. Lee
    • Department of SurgeryNew York Medical College
  • Keith Wendell
    • American Institute of Regeneration
    • Department of SurgeryNorth Shore University Hospital
  • Glenn Butler
    • Life Support Technology GroupMount Vernon Hospital Sound Shore Health System

DOI: 10.1007/BF02877766

Cite this article as:
Lee, B.Y., Wendell, K., Al-Waili, N. et al. Adv Therapy (2007) 24: 1202. doi:10.1007/BF02877766


This study was undertaken to investigate the efficacy of ultra-low microcurrent delivered by the Electro Pressure Regeneration Therapy (EPRT) device for the management of chronic wounds. In this study, 23 patients with chronic skin ulcers and 2 with abdominal dehiscence that was present for an average of 16.5 mo, who were not responsive to standard conservative treatment in a hospital setting, were treated with the EPRT device. Wounds were treated with direct current (maximum of 3 mA) of 1 polarity for 11.5 min and then with a current of the opposite polarity for another 11.5 min. Treatment was applied through ultra-low microcurrents (in the mA to nA range) conducted through special wraps applied above and below the wound. The results revealed that 34.8% of cases achieved complete wound healing after an average of 45.6 h of treatment, and 39.1 % achieved ≥50% healing after an average of 39.7 h of treatment. Several patients achieved significant results after 1 to 2 treatments. The EPRT device not only accelerated healing but also appeared to negate the effect of a person’s age on wound healing.


ultra-low microcurrentulcerwoundantioxidants
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© Health Communications Inc 2007