Iron store and free radicals in thalassemia
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Hyper-ferrous state is the result of multiple transfusions, whereby the iron excess in such conditions may be toxic to the organism. Patients suffering from thalassemia receive multiple transfusions. In the eastern part of India, both β0-thalassemia and heterozygous Eβ-thalassemia occur. This paper expresses the hyper-ferrous state, leading to iron overload in these two conditions and also reports the increased generation of free radicals, consequent to the iron overload.
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- Iron store and free radicals in thalassemia
Indian Journal of Clinical Biochemistry
Volume 20, Issue 2 , pp 192-194
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