Indian Journal of Clinical Biochemistry

, Volume 20, Issue 2, pp 192–194

Iron store and free radicals in thalassemia

  • K. Goswami
  • S. Ghosh
  • M. Bandyopadhyay
  • K. L. Mukherjee
Article

DOI: 10.1007/BF02867427

Cite this article as:
Goswami, K., Ghosh, S., Bandyopadhyay, M. et al. Indian J Clin Biochem (2005) 20: 192. doi:10.1007/BF02867427
  • 34 Downloads

Abstract

Hyper-ferrous state is the result of multiple transfusions, whereby the iron excess in such conditions may be toxic to the organism. Patients suffering from thalassemia receive multiple transfusions. In the eastern part of India, both β0-thalassemia and heterozygous Eβ-thalassemia occur. This paper expresses the hyper-ferrous state, leading to iron overload in these two conditions and also reports the increased generation of free radicals, consequent to the iron overload.

Key words

ThalassemiaFerritinMalondialdehyde

Copyright information

© Association of Clinical Biochemists of India 2005

Authors and Affiliations

  • K. Goswami
    • 1
  • S. Ghosh
    • 1
  • M. Bandyopadhyay
    • 1
  • K. L. Mukherjee
    • 1
  1. 1.Dept of BiochemistryVivekananda Institute of Medical SciencesKolkataIndia