Preventing the common cold with a vitamin C supplement: A double-blind, placebo-controlled survey
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
One hundred sixty-eight volunteers were randomized to receive a placebo or a vitamin C supplement, two tablets daily, over a 60-day period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. Compared with the placebo group, the active-treatment group had significantly fewer colds (37 vs 50, P<.05), fewer days challenged virally (85 vs 178), and a significantly shorter duration of severe symptoms (1.8 vs 3.1 days, P<.03). Consequently, volunteers in the active group were less likely to get a cold and recovered faster if infected. Few side effects occurred with the active treatment, and volunteers reported greatly increased satisfaction with the study supplement compared with any previous form of vitamin C. This well-tolerated vitamin C supplement may prevent the common cold and shorten the duration of symptoms. Volunteers were generally impressed by the protection afforded them during the winter months and the general acceptability of the study medication.
- Eccles R. Common Cold Centre, Cardiff, UK. Available at: http://www.cf.ac.uk/biosci/associates/ cold/home.html.
- Hemila H. Vitamin C intake and susceptibility to the common cold.Br J Nutr. 1997;77:59–72. CrossRef
- Hemila H. Vitamin C and common cold incidence: a review of studies with subjects under heavy physical stress.Int J Sports Med. 1996;17:379–383. CrossRef
- Hemila H. Vitamin C and the common cold.Br J Nutr. 1992;67:3–16. CrossRef
- Hemila H, Herman ZS. Vitamin C and the common cold: a retrospective analysis of Chalmers’ review.J Am Coll Nutr. 1995;14:116–123.
- Audera C, Patulny R, Sander B, Douglas R. Mega-dose vitamin C in treatment of the common cold: a randomised controlled trial.Med J Aust. 2001;175:359–362.
- Bush MJ, Verlangieri AJ. An acute study on the relative GI absorption of a novel form of calcium ascorbate.Res Commun Chem Pathol Pharmacol. 1987;57:137–140.
- Fay MJ, Verlangieri AJ. Stimulatory action of calcium threonate on ascorbic acid uptake by a human T-lymphoma cell line.Life Sci. 1994;49:1377–1381. CrossRef
- Josling PD. Preventing the common cold with a garlic supplement: a double-blind placebo-controlled survey.Adv Ther. 2001;18:189–193.
- Preventing the common cold with a vitamin C supplement: A double-blind, placebo-controlled survey
Advances in Therapy
Volume 19, Issue 3 , pp 151-159
- Cover Date
- Print ISSN
- Online ISSN
- Springer Healthcare Communications
- Additional Links
- common cold
- vitamin C
- Industry Sectors