Proceedings of the Indian Academy of Sciences - Chemical Sciences

, Volume 100, Issue 2, pp 81–90

One-pot, three-component, sequential Michael-Michael-ring-closure reactions. Annulation of meta-dicarboxylated aromatic rings. Total synthesis of juncunol

  • Gary H. Posner
  • Karen A. Canella
  • Ernest F. Silversmith
Special Issue on Organic Synthesis

DOI: 10.1007/BF02839442

Cite this article as:
Posner, G.H., Canella, K.A. & Silversmith, E.F. Proc. Indian Acad. Sci. (Chem. Sci.) (1988) 100: 81. doi:10.1007/BF02839442

Abstract

The preparative value of one-pot, multicomponent, sequential Michael-Michael-ring-closure reactions followed by aromatization is illustrated in two ways: (1) by a multi-gram example, and (2) by a total synthesis of juncunol, an unusual vinyldihydrophenanthrene.

Keywords

Sequential Michael-Michael-ring-closure reactionsone-pot reactionsbenzannulationsjuncunol

Copyright information

© Indian Academy of Sciences 1988

Authors and Affiliations

  • Gary H. Posner
    • 1
  • Karen A. Canella
    • 1
  • Ernest F. Silversmith
    • 1
  1. 1.Department of ChemistryThe Johns Hopkins UniversityBaltimoreUSA