New Drugs Antibiotics

The Indian Journal of Pediatrics

, Volume 73, Issue 4, pp 313-321

First online:

New antiviral agents

  • Nahed Abdel-HaqAffiliated withDivision of Infectious Diseases, Children's Hospital of MichiganCarman and Ann Adams Department of Pediatrics, Wayne State University, School of Medicine Email author 
  • , Pimpanada ChearskulAffiliated withDivision of Infectious Diseases, Children's Hospital of MichiganCarman and Ann Adams Department of Pediatrics, Wayne State University, School of Medicine
  • , Hossam Al-TatariAffiliated withDivision of Infectious Diseases, Children's Hospital of MichiganCarman and Ann Adams Department of Pediatrics, Wayne State University, School of Medicine
  • , Basim AsmarAffiliated withDivision of Infectious Diseases, Children's Hospital of MichiganCarman and Ann Adams Department of Pediatrics, Wayne State University, School of Medicine

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Abstract

During the last three decades, a better understanding of viral replication and disease states caused by viral infections have led to the development of newer antiviral agents with enhanced activity and better tolerability. This review focuses on newer systemic and topical antiviral agents that are used in treatment of herpes viruses including herpes simplex type-1 (HSV-1) and type-2 (HSV-2), varicella-zoster virus (VZV) and cytomegalovirus CMV) as well as the human papilloma virus (HPV). Included in this article are the agents famiclovir, penciclovir, valganciclovir, imiquimod, docosanole and brivudin.

Key words

Viral infecting Systemic and topical antiviral agents Herpes viruses