In Vitro

, Volume 18, Issue 6, pp 531–537

Cholera toxin stimulation of human mammary epithelial cells in culture

  • Martha R. Stampfer

DOI: 10.1007/BF02810076

Cite this article as:
Stampfer, M.R. In Vitro Cell.Dev.Biol.-Plant (1982) 18: 531. doi:10.1007/BF02810076


Addition of cholera toxin to human mammary epithelial cultures derived from reduction mammoplasties and primary carcinomas greatly stimulated cell growth and increased the number of times the cells could be successfully subcultured. Other agents known to increase intracellular cAMP levels were also growth stimulatory. The increased growth potential conferred by cholera toxin enhances the usefulness of this cell culture system.

Key words

cholera toxinhuman mammary epithelial cells

Copyright information

© Tissue Culture Association, Inc 1982

Authors and Affiliations

  • Martha R. Stampfer
    • 1
    • 2
  1. 1.Peralta Cancer Research Institute, Paralta HospitalOakland
  2. 2.Donner Laboratory, Lawrence Berkeley LaboratoryBerkeley