Biological Trace Element Research

, Volume 55, Issue 3, pp 297–305

Effect of chromium nicotinic acid supplementation on selected cardiovascular disease risk factors

  • Vicky L. K. Thomas
  • Sareen S. Gropper

DOI: 10.1007/BF02785287

Cite this article as:
Thomas, V.L.K. & Gropper, S.S. Biol Trace Elem Res (1996) 55: 297. doi:10.1007/BF02785287


The effects of daily supplemental chromium (200 μg) complexed with 1.8 mg nicotinic acid on plasma glucose and lipids, including total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides, were assessed in 14 healthy adults and 5 adults with noninsulin-dependent diabetes mellitus (NIDDM) using a double-blind crossover study with 8-wk experimental periods. Eight of the 14 healthy subjects and all 5 subjects with NIDDM also underwent an oral glucose tolerance test with assessment of 90 min postprandial plasma glucose and insulin concentrations. No statistically significant effects of chromium nicotinic acid supplementation were found on plasma insulin, glucose, or lipid concentrations, although chromium nicotinic acid supplementation slightly lowered fasting plasma total and LDL cholesterol, triglycerides, and glucose concentrations, and 90-min postprandial glucose concentrations in individuals with NIDDM.

Index Entries

Chromiumglucoselipidshealthy adultsnon-insulin-dependent diabetes

Copyright information

© Humana Press Inc. 1997

Authors and Affiliations

  • Vicky L. K. Thomas
    • 1
  • Sareen S. Gropper
    • 2
  1. 1.TADC-DPH-SPUS Army Personnel CommandAlexandria
  2. 2.Department of Nutrition and Food ScienceAuburn University