Biological Trace Element Research

, Volume 62, Issue 3, pp 167–182

Preparation of hair for measurement of elements by inductively coupled plasma-mass spectrometry (ICP-MS)

Authors

  • Richard F. Puchyr
    • Doctor’s Data Inc.
  • Dean A. Bass
    • Doctor’s Data Inc.
  • Rob Gajewski
    • Doctor’s Data Inc.
  • Mishelle Calvin
    • Doctor’s Data Inc.
  • William Marquardt
    • Doctor’s Data Inc.
  • Karen Urek
    • Doctor’s Data Inc.
  • Mary Ellen Druyan
    • Doctor’s Data Inc.
  • David Quig
    • Doctor’s Data Inc.
Article

DOI: 10.1007/BF02783969

Cite this article as:
Puchyr, R.F., Bass, D.A., Gajewski, R. et al. Biol Trace Elem Res (1998) 62: 167. doi:10.1007/BF02783969

Abstract

The preparation of hair for the determination of elements is a critical component of the analysis procedure. Open-beaker, closedvessel microwave, and flowthrough microwave digestion are methods that have been used for sample preparation and are discussed. A new digestion method for use with inductively coupled plasma-mass spectrometry (ICP-MS) has been developed. The method uses 0.2 g of hair and 3 mL of concentrated nitric acid in an atmospheric pressurelow-temperature microwave digestion (APLTMD) system. This preparation method is useful in handling a large numbers of samples per day and may be adapted to hair sample weights ranging from 0.08 to 0.3 g. After digestion, samples are analyzed by ICP-MS to determine the concentration of Li, Be, B, Na, Mg, Al, P, S, K, Ca, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ge, As, Se, Rb, Sr, Zr, Mo, Pd, Ag, Cd, Sn, Sb, I, Cs, Ba, Pt, Au, Hg, Tl, Pb, Bi, Th, and U. Benefits of the APLTMD include reduced contamination and sample handling, and increased precision, reliability, and sample throughput.

Index Entries

Hair elements Li, Be, B, Na, Mg, AI, P, S, K, Ca, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ge, As, Se, Rb, Sr, Zr, Mo, Pd, Ag, Cd, Sn, Sb, I, Cs, Ba, Pt, Au, Hg, Tl, Pb, Bi, Th, and Umicrowave digestionICP-MS

Copyright information

© Humana Press Inc. 1998