Infection

, Volume 26, Issue 1, pp 58–60

Clinical and biochemical reactivation of HBV infection in a thalassemic patient after bone marrow transplantation

  • S. Li Volti
  • G. Pizzarelli
  • M. Galimberti
  • F. Di Gregorio
  • M. A. Romeo
  • G. Lucarelli
  • G. Russo
Case Report

DOI: 10.1007/BF02768759

Cite this article as:
Volti, S.L., Pizzarelli, G., Galimberti, M. et al. Infection (1998) 26: 58. doi:10.1007/BF02768759

Summary

The case of a young man effected by homozygous beta-thalassemia is reported who had serologic findings of a prior HBV infection and who presented with clinical and biochemical acute HBV infection probably caused by HBV reactivation after allogeneic bone marrow transplantation. The patient's clinical history suggests that HBV can persist without serological findings of HBsAg and HBV-DNA in persons previously infected by HBV and that HBV reactivation can occur 2 years after allogeneic bone marrow transplantation, as a result of immunosuppressive therapy or an HCV activation.

Copyright information

© MMV Medizin Verlag GmbH München 1998

Authors and Affiliations

  • S. Li Volti
    • 1
  • G. Pizzarelli
    • 1
  • M. Galimberti
    • 2
  • F. Di Gregorio
    • 1
  • M. A. Romeo
    • 1
  • G. Lucarelli
    • 2
  • G. Russo
    • 1
  1. 1.I Istituto di Clinica Pediatrica dell'Università di CataniaCataniaItaly
  2. 2.Divisione Ematologica e Centro Trapianto di Midollo Osseo di MuragliaOspedale di PesaroItaly