The Indian Journal of Pediatrics

, Volume 62, Issue 3, pp 345–351

Enteric viral infections in pre-school children in Karachi, Pakistan

Authors

  • Mubina Agboatwalla
    • Department of Pediatrics, Unit-IICivil Hospital
  • Shin Isomura
    • Department of Medical Zoology, School of MedicineNagoya University
  • Dure-Samin Akram
    • Department of Pediatrics, Unit-IICivil Hospital
  • Yuichi Isihara
    • Department of VirologyAichi Prefectural Institute of Public Health
  • Kenji Sakae
    • Department of VirologyAichi Prefectural Institute of Public Health
  • Teruo Yamashita
    • Department of VirologyAichi Prefectural Institute of Public Health
  • Osamu Nishuo
    • Department of VirologyAichi Prefectural Institute of Public Health
Original Article

DOI: 10.1007/BF02753600

Cite this article as:
Agboatwalla, M., Isomura, S., Akram, D. et al. Indian J Pediatr (1995) 62: 345. doi:10.1007/BF02753600

Abstract

A prospective study was conducted in Karachi, Pakistan on the virology of enteropathogens excreted by children with acute gastroenteritis and the results were compared with a control group of healthy children. Rotavirus and Adenovirus detection was done using ELISA techniques, while enterovirus isolation was done by virus culture. In 1990, 12.3% children with acute watery diarrhoea excreted rotavirus, as compared to 24.4% children in 1991. None of the healthy children excreted adenovirus 40 and 41. Preliminary results of 1992 revealed that rotavirus was seen in 13% of children with acute watery diarrhoea and adenovirus in 10% of children. Enteroviruses were isolated in the same frequency in all three groups i.e. children with acute watery diarrhoea, children with poliomyelitis and healthy children. Non-polio enteroviruses were excreted in 50–52% in all the 3 groups. The rate of enterovirus excretion is much higher than seen in other developed countries and is the same in children with diarrhoea and healthy children.

Key words

AdenovirusRotavirusAcute gastroenteritisAcute poliomyelitis

Copyright information

© Dr. K C Chaudhuri Foundation 1995