, Volume 68, Issue 8, pp 715-717

Neonatal Sepsis:Staphylococcus aureus as the predominant pathogen

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96 consecutive inborn neonates with blood culture proven bacterial sepsis during the period January to June 1997 were studied. Lethargy with refusal of feeds (28%), fever (28%) and respiratory distress (31.3%) were the major presenting features. Half of them (n=48) were of early onset (<48 hours) and the remaining half were of late onset (> 48 hours). Staphylococcus aureus (n=59, 61.5%) was the predominant pathogen and 66% of them were methicillin resistant followed by Klebsiella pnemoniae (n=24, 21.9), Escherichia coli (n=13, 13.5%) and streptococci (n=3, 3.1%). Antibiotic resistance was common, with the sensitivity to various antibiotics being ampicillin 19%, gentamicin 21.6%, cefotaxime 32.8%, amikacin 50%, chloromycetin 59.6% and ciprofloxacin 90.3%.