Clinical Reviews in Allergy & Immunology

, Volume 17, Issue 4, pp 401–412

Allergic emergencies in the Physician’s office

  • Paul A. Greenberger
Allergic Emergencies

DOI: 10.1007/BF02737645

Cite this article as:
Greenberger, P.A. Clinic Rev Allerg Immunol (1999) 17: 401. doi:10.1007/BF02737645


Allergen immunotherapy may result in anaphylaxis without previous warning signs, such as a previous systemic reaction. Large local reactions are not predictive of future systemic reactions based on several published studies. Emergency medications and equipment should be kept current, and emergency preparedness by staff must be a priority. The overall rarity of severe anaphylaxis in a physician’s office may create a sense of false security. Staff should know when to call for emergency help, and it is advised that they inform the physician immediately of all immunotherapy systemic reactions. Early administration of sc epinephrine will help control and stop most but not all systemic reactions to injection therapy.

Copyright information

© Humana Press Inc 1999

Authors and Affiliations

  • Paul A. Greenberger
    • 1
    • 2
  1. 1.Division of Allergy-Immunology, Department of MedicineNorthwestern University Medical SchoolChicago
  2. 2.Ernest S. Bazley Asthma and Allergic Diseases CenterNorthwestern University Medical SchoolChicago