Current HIV/AIDS Reports

, Volume 3, Issue 3, pp 132–138

Solid organ transplantation is a reality for patients with HIV infection

Article

DOI: 10.1007/BF02696657

Cite this article as:
Roland, M.E. & Stock, P.G. Curr HIV/AIDS Rep (2006) 3: 132. doi:10.1007/BF02696657

Abstract

Recent policies, guidelines, and laws reflect promising preliminary outcomes among transplant recipients with HIV infection, and ethical analyses suggest that it is not justifiable to deny solid organ transplantation based solely on HIV-infection status. These studies consistently describe stable HIV disease following liver and kidney transplantation. Despite good graft survival, kidney allograft rejection occurs frequently, and serious non-AIDS-defining infections requiring hospitalization are common following antirejection therapy. Profound interactions between immunosuppressants and antiretroviral drugs require careful monitoring, dose adjustment, and highly effective communication between the patient and a multidisciplinary group of health care providers. Despite these scientific and policy advances, many health care providers and patients remain unaware of ongoing progress in this field. The implications are critical, as late referral for liver transplant evaluation increases the pretransplant mortality risk. Because important patient selection and clinical management questions remain, it is critical that ongoing studies are completed quickly.

Copyright information

© Current Science Inc 2006

Authors and Affiliations

  1. 1.Department of Medicine, Positive Health Program (AIDS Division) at San Francisco General HospitalUniversity of CaliforniaSan FranciscoUSA