Osteoporosis International

, Volume 7, Issue 6, pp 533–538

Associations of vitamin C, calcium and protein with bone mass in postmenopausal Mexican American women

Authors

    • Division of Epidemiology, Department of Health Research and PolicyStanford University School of Medicine
  • M. Luz Villa
    • Department of MedicineStanford University School of Medicine
    • Department of the Muskuloskeletal Research LaboratoryGeriatric Research, Education, and Clinical Center, Veteran Affairs Medical Center
  • R. Marcus
    • Department of MedicineStanford University School of Medicine
    • Department of the Muskuloskeletal Research LaboratoryGeriatric Research, Education, and Clinical Center, Veteran Affairs Medical Center
  • J. L. Kelsey
    • Division of Epidemiology, Department of Health Research and PolicyStanford University School of Medicine
    • Department of the Muskuloskeletal Research LaboratoryGeriatric Research, Education, and Clinical Center, Veteran Affairs Medical Center
Original Article

DOI: 10.1007/BF02652558

Cite this article as:
Wang, M.-., Luz Villa, M., Marcus, R. et al. Osteoporosis Int (1997) 7: 533. doi:10.1007/BF02652558

Abstract

We investigated the associations of vitamin C, calcium and protein intakes with bone mass at the femoral neck and lumbar spine in postmenopausal Mexican American women. Bone mass was measured by dual-energy X-ray absorptiometry (DXA) and expressed as areal (BMD, g/cm2) and volumetric (bone mineral apparent density or BMAD, g/cm3) bone mineral density. Diet was assessed using a modified version of the National Cancer Institute Food Questionnaire, which was administered by trained bilingual interviewers familiar with Mexican dietary practices. Data gathered from 125 subjects were analyzed using multiple linear regression analysis with age, body mass index (BMI), acculturation, years of estrogen use, physical activity, total energy intake, and the nutrient of interest as independent variables. Neither calcium nor calcium/protein ratio was associated with bone mineral density. There was evidence of a positive association between dietary vitamin C intake and femoral neck BMD (β=0.0002 g/cm2 per mg/day, SE=0.0001,p=0.07) and BMAD (β=0.0001 g/cm3 per mg/day, SE=0.00006,p<0.05), but vitamin C was not associated with lumbar spine bone mass. Further investigation of the role of vitamin C in skeletal health is warranted.

Keywords

AcculturationBone massDietMexican AmericanPostmenopausal womenVitamin C

Copyright information

© European Foundation for Osteoporosis and the National Osteoporosis Foundation 1997