Journal of the American Oil Chemists Society

, Volume 24, Issue 4, pp 127–129

The rates of oxidation of unsaturated fatty acids and esters

  • Ralph T. Holman
  • Otto C. Elmer

DOI: 10.1007/BF02643258

Cite this article as:
Holman, R.T. & Elmer, O.C. J Am Oil Chem Soc (1947) 24: 127. doi:10.1007/BF02643258


The rates of autoxidation of oleic acid, ethyl oleate, linoleic acid, 10,12-linoleic acid, ethyl linoleate, trilinolein, pentaerythritol linoleate, dipentaerythritol linoleate, elaidolinolenic acid, linolenic acid, ethyl linolenate, trilinolenin, and methyl arachidonate have been studied by oxygen uptake in a Warburg respirometer and the results are compared with the rates of enzymatic oxidation of lipoxidase substrates.

The increase in the number of double bonds in a fatty acid by one increases the rate of oxidation of the fatty acid or its esters by at least a factor or two.

Earlier findings that acids oxidize more rapidly than their esters have been confirmed.

The initial rates of lipoxidase oxidation of ethyl linoleate, ethyl linolenate, and methyl arachidonate were found to be essentially the same.

Copyright information

© The American Oil Chemists' Society 1947

Authors and Affiliations

  • Ralph T. Holman
    • 1
  • Otto C. Elmer
    • 1
  1. 1.The Department of Physiological ChemistryUniversity of MinnesotaMinneapolis
  2. 2.Biokemiska AvdelningenMedicinska NobelinstitutetStockholmSweden