, Volume 20, Issue 11, pp 856-858

Use of cyclosporin a in establishing epstein-barr virus-transformed human lymphoblastoid cell lines

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Summary

We have investigated the potential for using cyclosporin A to increase the efficiency with which Epstein-Barr virus-transformed human lymphoblast lines can be prepared. Use of this immunosuppressive drug has permitted the development of a procedure with success rates exceeding 95% despite the processing of very large numbers of samples.

This work was supported by National Institute of Neurological and Communicative Disorders and Stroke Grants NS16367 (Huntington's Disease Center Without Walls) and NS 20012.