Calcified Tissue International

, Volume 45, Issue 1, pp 12–14

The effects of muscle-building exercise on bone mineral density of the radius, spine, and hip in young men

Authors

  • Laura A. Colletti
    • Veterans Administration Medical Center and Departments of Medicine, Radiology, and PharmacologyMedical University of South Carolina
  • Jeanne Edwards
    • Veterans Administration Medical Center and Departments of Medicine, Radiology, and PharmacologyMedical University of South Carolina
  • Leonie Gordon
    • Veterans Administration Medical Center and Departments of Medicine, Radiology, and PharmacologyMedical University of South Carolina
  • Judith Shary
    • Veterans Administration Medical Center and Departments of Medicine, Radiology, and PharmacologyMedical University of South Carolina
  • Norman H. Bell
    • Veterans Administration Medical Center and Departments of Medicine, Radiology, and PharmacologyMedical University of South Carolina
Clinical Investigations

DOI: 10.1007/BF02556654

Cite this article as:
Colletti, L.A., Edwards, J., Gordon, L. et al. Calcif Tissue Int (1989) 45: 12. doi:10.1007/BF02556654

Summary

We previously demonstrated that muscle-building exercise is associated with increases in serum Gla-protein, serum 1,25(OH)2D, and urinary cyclic AMP. These studies were interpreted to mean that this form of exercise increases bone formation and modifies the vitamin D-endocrine system to provide more calcium for bone. The present investigation was carried out in normal young adult white men to determine the effects of exercise on bone mineral density at weight-bearing and nonweight-bearing sites. Twelve men who had regularly engaged in muscle-building exercises (use of weights, exercise machines, or both) for at least 1 year and 50 age-matched controls (aged 19–40 years) were studied. The body weights of the two groups were not different from each other (78±2 vs. 74±1 kg, NS). Bone mineral density (BMD) of the lumbar spine, trochanter, and femoral neck was measured by dual-photon absorptiometry, and BMD of the midradius was measured by single-photon absorptiometry. It was found that muscle-building exercise was associated with increased BMD at the lumbar spine (1.35±0.03 vs. 1.22±0.02 g/cm2,P<0.01), trochanter (0.99±0.04 vs. 0.86±0.02 g/cm2,P<0.01), and femoral neck (1.18 ±0.03 vs. 1.02±0.02 g/cm2,P<0.001) but not at the midradius (0.77±0.02 vs. 0.77±0.01 g/cm2, NS). These studies provide additional evidence that muscle-building exercise is associated with increases in BMD at weight-bearing sites but not at nonweight-bearing sites.

Key words

ExerciseBone mineral densityRadiusHipSpine
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Copyright information

© Springer-Verlag New York Inc. 1989