Calcified Tissue International

, Volume 39, Issue 2, pp 63–68

Nonmineralized and mineralized bone collagen in bone of immobilized monkeys

Authors

  • Gerald L. Mechanic
    • Dental Research Center, Department of Biochemistry and NutritionUniversity of North Carolina at Chapel Hill
    • Department of SurgeryUniversity of North Carolina at Chapel Hill
  • Donald R. Young
    • Biomedical Research Division, Ames Research CenterNASA
  • Albert J. Banes
    • Dental Research Center, Department of Biochemistry and NutritionUniversity of North Carolina at Chapel Hill
    • Department of SurgeryUniversity of North Carolina at Chapel Hill
  • Mitsuo Yamauchi
    • Dental Research Center, Department of Biochemistry and NutritionUniversity of North Carolina at Chapel Hill
    • Department of SurgeryUniversity of North Carolina at Chapel Hill
Laboratory Investigations

DOI: 10.1007/BF02553292

Cite this article as:
Mechanic, G.L., Young, D.R., Banes, A.J. et al. Calcif Tissue Int (1986) 39: 63. doi:10.1007/BF02553292

Summary

Monkey bones from different time periods of immobilization and reambulation of the monkeys were assessed histologically. The bone was also assessed biochemically for nonmineralized collagen in bone. Results indicate that more non-mineralized bone is present in monkeys that have been immobilized, and upon reambulation, these values tend to be normalized to control bone.

Key words

BoneCollagenOsteoporosis

Copyright information

© Springer-Verlag New York Inc. 1986