Murray, A. & Marjanovic, D. Med. Biol. Eng. Comput. (1997) 35: 425. doi:10.1007/BF02534102
The authors use photoelectric plethysmography to determine the external occlusion pressure for blood vessels in human tissue in vivo. Three wavelengths are employed; 950 nm (infra-red), 640 nm (red) and 583 nm (yellow). Each probe is applied in turn to one finger of each subject. Pressure is applied, using a neonatal blood pressure cuff, to the finger via the probe. This pressure is increased linearly to 20 kPa (150 mmHg) over 15 s and then decreased linearly to zero over 15 s. The pressure at which perfusion returns is obtained for four repeat measurements at each wavelength. The mean (±standard deviation) occlusion pressures for all 13 subjects investigated are 7.1(±1.9) kPa for infra-red, 6.3(±1.7) kPa for red and 5.8(±1.8) kPa for yellow. The pressure is 0.79(±0.83) kPa lower for red compared with infra-red (P<0.01), 0.54(±0.60) kPa lower for yellow compared with red (P<0.002) and 1.3(±1.0) kPa lower for yellow compared with infra-red (P<0.005). The reduced penetration of shorter optical wavelengths can be used to detect the lower occlusion pressures of the smaller blood vessels nearer the skin surface.
Pulse Photoelectric plethysmography Perfusion Capillary bed Interface pressure Occlusion pressure