, Volume 64, Issue 1-2, pp 267-272

A new method for the preparation of68Ga-generators following proton bombardment of gallium oxide targets

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A method of preparing a68Ge/68Ga generator directly from an irradiated target of Ga2O3 is discussed, which utilises an ion exchange column containing hydrous zirconium oxide (HZO). A yield of 30–40% of68Ga is reported with a breakthrough of68Ge as low as one part in 105. The leakage of stable zirconium from the column may be a problem for routine clinical use and this is being investigated further.