Population Genetics

Bulletin of Mathematical Biology

, Volume 52, Issue 1, pp 209-240

First online:

A mathematical theory of natural and artificial selection—I

  • J. B. S. HaldaneAffiliated withTrinity College

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Mathematical expressions are found for the effect of selection on simple Mendelian populations mating at random. Selection of a given intensity is most effective when amphimixis does not affect the character selected, e.g. in complete inbreeding or homogamy. Selection is very ineffective on autosomal recessive characters so long as they are rare.