European Journal of Clinical Microbiology and Infectious Diseases

, Volume 16, Issue 8, pp 568–574

Increasing incidence of nosocomialChryseobacterium indologenes infections in Taiwan

  • P. R. Hsueh
  • L. J. Teng
  • P. C. Yang
  • S. W. Ho
  • W. C. Hsieh
  • K. T. Luh
Article

DOI: 10.1007/BF02447918

Cite this article as:
Hsueh, P.R., Teng, L.J., Yang, P.C. et al. Eur. J. Clin. Microbiol. Infect. Dis. (1997) 16: 568. doi:10.1007/BF02447918

Abstract

To understand the clinical features, antimicrobial therapy, and epidemiology ofChryseobacterium indologenes infections, the medical records of 36 patients with nosocomialChryseobacterium indologenes infections seen over a three-year period at National Taiwan University Hospital were reviewed. The 36 isolates recovered from these patients were studied by molecular typing and determination of antimicrobial susceptibility patterns. Nine patients had underlying neoplastic diseases, seven had diabetes mellitus, five had burn wounds, and four had uremia. The clinical syndrome included ten patients with intraabdominal infections, nine with wound sepsis, six with intravascular catheter-related bacteremia, and four with ventilator-associated pneumonia. Thirteen patients had monomicrobial bacteremia, and four had polymicrobial bacteremia. Nineteen patients (53%) developed infections associated with various indwelling devices. The deaths of five patients (14%) were directly attributable to infection withChryseobacterium indologenes. All isolates recovered showed a wide range of resistance to commonly used antimicrobial agents. The random amplified polymorphic DNA (RAPD) patterns of the isolates differed from each other, indicating the absence of epidemiological relatedness among these isolates. Nosocomial infection caused by multiresistantChryseobacterium indologenes appears to be an emerging problem in Taiwan and should be studied further.

Copyright information

© MMV Medizin Verlag GmbH 1997

Authors and Affiliations

  • P. R. Hsueh
    • 1
    • 2
  • L. J. Teng
    • 1
    • 3
  • P. C. Yang
    • 2
  • S. W. Ho
    • 1
    • 3
  • W. C. Hsieh
    • 2
  • K. T. Luh
    • 1
    • 2
  1. 1.Department of Laboratory MedicineNational Taiwan University HospitalTaipei 100Taiwan
  2. 2.Department of Internal MedicineNational Taiwan University HospitalTaipei 100Taiwan
  3. 3.School of Medical TechnologyNational Taiwan UniversityTaipeiTaiwan