Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 5, pp 1071–1073

Extremely low doses of oxytocin reduce pain sensitivity in men

  • Yu. V. Uryvaev
  • G. A. Petrov
Physiology

DOI: 10.1007/BF02447648

Cite this article as:
Uryvaev, Y.V. & Petrov, G.A. Bull Exp Biol Med (1996) 122: 1071. doi:10.1007/BF02447648

Abstract

The effect of extremely low doses of oxytocin (vapor) on the perception of pain (pricking of the finger) is studied on 48 healthy volunteers. Inhalation of oxytocin vapor from the standard solution in doses producing a sensation of smell lowers pain threshold by 56.5%. Inhalation of oxytocin vapor creating no sense of smell has a lower hypalgesic effect. The oxytocin-induced hypalgesia is consistent with reduction in the heart reactivity to pain.

Key Words

oxytocinhypalgesiapain

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • Yu. V. Uryvaev
    • 1
    • 2
  • G. A. Petrov
    • 1
    • 2
  1. 1.Department of Normal PhysiologyI. M. Sechenov Moscow Medical AcademyMoscowUSSR
  2. 2.Department of Normal PhysiologyTver' Medical AcademyMoscowUSSR