Chromatographia

, Volume 28, Issue 3, pp 126–128

Preparative isolation of (+)-beta-eudesmol fromAmyris balsamifera

  • T. A. van Beek
  • R. Kleis
  • G. P. Lelyveld
  • AE. de Groot
Originals

DOI: 10.1007/BF02319632

Cite this article as:
van Beek, T.A., Kleis, R., Lelyveld, G.P. et al. Chromatographia (1989) 28: 126. doi:10.1007/BF02319632

Summary

Optically pure (+)-beta-eudesmol is a possible starting material for the synthesis of several termite defense compounds. A two step procedure for the isolation of gram quantities of (+)-beta-eudesmol from commercially availableAmyris balsamifera oil (syn. West Indian sandalwood oil), containing 8% beta-eudesmol, was developed. Step one consisted of an efficient vacuum distillation of the total oil. Step two was a medium pressure LC separation with an AgNO3 impregnated silica gel stationary phase. Several other separation procedures failed due to the presence of many closely related sesquiterpene alcohols (75% of the oil).

Key Words

Column liquid chromatographyPreparative isolation(+)-Beta-eudesmolAmyris balsamifera

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1989

Authors and Affiliations

  • T. A. van Beek
    • 1
  • R. Kleis
    • 1
  • G. P. Lelyveld
    • 1
  • AE. de Groot
    • 1
  1. 1.Department of Organic Chemistry, Phytochemical SectionAgricultural UniversityWageningenThe Netherlands