Annals of Surgical Oncology

, Volume 2, Issue 5, pp 392–399

Resection of brain metastases from sarcoma

  • Marek Wroński
  • Ehud Arbit
  • Michael Burt
  • Georgio Perino
  • Joseph H. Galicich
  • Murray F. Brennan
Original Articles

DOI: 10.1007/BF02306371

Cite this article as:
Wroński, M., Arbit, E., Burt, M. et al. Annals of Surgical Oncology (1995) 2: 392. doi:10.1007/BF02306371

Abstract

Background: Brain metastases from sarcoma are rare, and data concerning the treatment and results of therapy are sparse.

Methods: We retrospectively reviewed 25 patients with brain metastases from sarcoma of skeletal or soft-tissue origin, surgically treated in a single institution during 20 years.

Results: In 18 patients the brain lesion was located supratentorially, and in 7 patients infratentorially. Median age at brain metastasis diagnosis was 25 years. Median time from primary diagnosis to diagnosis of brain metastasis was 26.7 months. Lung metastases were present in 19 patients and in 8 patients they were synchronous with the brain lesion. Pulmonary metastases were resected in 12 patients (48% of total, and 63% of those with pulmonary lesions). The overall median survival from diagnosis of the primary sarcoma was 38 months and from craniotomy was 7 months. The presence or absence of lung lesions did not alter the median survival as calculated from diagnosis of brain metastasis. Overall percent survival was 40% at 1 year and 16% at 2 years.

Conclusions: Because brain metastases from sarcoma are refractory to alternative treatment, surgical excision is indicated when feasible. Brain metastases from sarcoma are uncommon, usually occurring with or after lung metastasis. Long-term survival is possible in some patients.

Key Words

Brain metastasis Sarcoma Brain neoplasms 

Copyright information

© The Society of Surgical Oncology, Inc 1995

Authors and Affiliations

  • Marek Wroński
    • 4
  • Ehud Arbit
    • 4
  • Michael Burt
    • 1
  • Georgio Perino
    • 3
  • Joseph H. Galicich
    • 4
  • Murray F. Brennan
    • 2
  1. 1.Thoracic ServiceMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  2. 2.Gastric and Mixed Tumor Service of Department of SurgeryMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  3. 3.Department of PathologyMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  4. 4.Neurosurgery ServiceMemorial Sloan-Kettering Cancer CenterNew YorkUSA

Personalised recommendations