Annals of Surgical Oncology

, Volume 5, Issue 7, pp 620–626

Presentation, treatment, and outcome of local recurrence after skin-sparing mastectomy and immediate breast reconstruction

  • Lisa A. Newman
  • Henry M. Kuerer
  • Kelly K. Hunt
  • Stephen S. Kroll
  • Frederick C. Ames
  • Merrick I. Ross
  • Barry W. Feig
  • S. Eva Singletary
Original Articles

DOI: 10.1007/BF02303832

Cite this article as:
Newman, L.A., Kuerer, H.M., Hunt, K.K. et al. Annals of Surgical Oncology (1998) 5: 620. doi:10.1007/BF02303832

Abstract

Background: The local recurrence (LR) rate with skin-sparing mastectomy (SSM) and immediate breast reconstruction (IBR) has been reported as comparable to the LR rate after conventional mastectomy. However, limited data are available on the prognostic significance and management of LR following SSM.

Methods: A prospective database maintained at the University of Texas M. D. Anderson Cancer Center identified 437 SSMs performed for 372 invasive T1/T2 breast cancers between 1986 and 1993.

Results: Twenty-three LRs were identified, with a LR rate of 6.2% (23/372). Twenty-two of these (96%) presented as palpable skin-flap masses. The median time to recurrence was 25 months (range, 3 to 98 months). Fourteen patients were treated with a combination of surgery and systemic therapy. Resection of the reconstructed breast was performed in only three patients. Complete local control of the recurrent disease was achieved in 17 patients (74%). Nine patients (39%) developed distant metastatic disease. At a median follow-up of 26 months, 14 of 23 patients (61%) are alive without evidence of disease, and 7 (30%) have died from breast cancer.

Conclusions: Because LR rate with SSM is low and likelihood of local control and survival is high, SSM and IBR is an acceptable treatment option for early stage breast cancer.

Key Words

Early stage breast cancerImmediate breast reconstructionSkin-sparing mastectomy

Copyright information

© The Society of Surgical Oncology, Inc. 1998

Authors and Affiliations

  • Lisa A. Newman
    • 2
  • Henry M. Kuerer
    • 2
  • Kelly K. Hunt
    • 2
  • Stephen S. Kroll
    • 1
  • Frederick C. Ames
    • 2
  • Merrick I. Ross
    • 2
  • Barry W. Feig
    • 2
  • S. Eva Singletary
    • 2
  1. 1.Department of Plastic and Reconstructive SurgeryThe University of Texas M. D. Anderson Cancer CenterHouston
  2. 2.Dept. of Surgical OncologyThe University of Texas M. D. Anderson Cancer CenterHouston