Annals of Surgical Oncology

, Volume 5, Issue 3, pp 220–226

Use of touch preps for diagnosis and evaluation of surgical margins in breast cancer

  • V. Suzanne Klimberg
  • Kent C. Westbrook
  • Soheila Korourian
Original Articles

DOI: 10.1007/BF02303776

Cite this article as:
Klimberg, V.S., Westbrook, K.C. & Korourian, S. Annals of Surgical Oncology (1998) 5: 220. doi:10.1007/BF02303776

Abstract

Background: The best cosmetic results with conservative breast surgery are obtained at the time of initial excisional biopsy. The usefulness of the touch prep (TP) technique was evaluated for accuracy in diagnosis as well as in evaluation of margins at the time of original breast biopsy.

Methods: Four hundred twenty-eight consecutive patients with breast masses seen from January 1993 to December 1994 were evaluated prospectively using TP.

Results: Three hundred forty-five benign and 83 malignant tumors were evaluated. Tumors ranged in size from microscopic to 8 cm. Pathologic diagnosis was correct as compared to permanent section in 99.3%. The three carcinomas missed on TP were focal and in situ. Sensitivity was 96.39%, and specificity was 100%. Positive predictive value was 100%, and negative predictive value was 99.3%. For margin evaluation, the sensitivity and specificity were both estimated to be 100%.

Conclusions: TP has the advantage of being a simple, quick (2 to 3 minutes), safe (no loss of diagnostic material), and accurate method for diagnosis and estimation of tumor margins at the time of the original surgery.

Key Words

Touch prep Breast cancer Diagnosis Margins 

Copyright information

© The Society of Surgical Oncology, Inc. 1998

Authors and Affiliations

  • V. Suzanne Klimberg
    • 1
    • 2
  • Kent C. Westbrook
    • 1
  • Soheila Korourian
    • 2
  1. 1.From the Department of SurgeryUniversity of Arkansas for Medical Sciences, Arkansas Cancer Research CenterLittle Rock
  2. 2.the Department PathologyUniversity of Arkansas for Medical Sciences, Arkansas Cancer Research CenterLittle Rock

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