Clinical Rheumatology

, Volume 11, Issue 4, pp 498–501

Renal excretion of urate by hyperuricaemic-hyperlipidemic patients

  • E. Collantes Estevéz
  • F. J. Tinahones Madueño
  • A. González Ruiz
  • J. Añón Barbudo
  • M. Pineda Priego
  • P. Sánchez Guijo
Originals

DOI: 10.1007/BF02283105

Cite this article as:
Estevéz, E.C., Madueño, F.J.T., Ruiz, A.G. et al. Clin Rheumatol (1992) 11: 498. doi:10.1007/BF02283105

Summary

We studied the renal urate excretory function in two groups of hyperuricaemic male patients composed of individuals with associated hyperlipidemia and hyperuricaemic-normolipidemic individuals, respectively. Both the hyperlipidemia and the hyperuricaemia were primary inasmuch as none of the patients studied was obese or had an above-normal alcohol intake or blood hypertension. The results obtained show that hyperuricaemic-hyperlipidemic patients have higher serum levels of uric acid and poorer urate excretion as reflected in smaller clearance and fractioned excretion of the metabolite than hyperuricaemic-normolipidemic patients. This, in turn, suggests the occurrence of differences in the extent of the urate handling anomalies between the two groups of patients.

Key words

HyperuricaemiaHyperlipidemiaRenal Urate Excretion

Copyright information

© Acta Medica Belgica 1992

Authors and Affiliations

  • E. Collantes Estevéz
    • 1
    • 2
  • F. J. Tinahones Madueño
    • 1
  • A. González Ruiz
    • 1
  • J. Añón Barbudo
    • 1
  • M. Pineda Priego
    • 3
  • P. Sánchez Guijo
    • 1
  1. 1.Unidad Docente de Patología General, Departamento de MedicinaUniversidad de CórdobaSpain
  2. 2.Sección de ReumatologiaHospital UniversitarioCórdobaSpain
  3. 3.Departamento de Bioquímica, Biología Molecular y FisiologíaUniversidad de CórdobaCórdobaSpain
  4. 4.Departamento de MedicinaFacultad de MedicinaCórdobaSpain