Clinical Autonomic Research

, Volume 10, Issue 2, pp 69–75

Baroreceptor denervation presenting as part of a vagal mononeuropathy

  • D. L. Jardine
  • I. C. Melton
  • S. I. Bennett
  • I. G. Crozier
  • I. M. Donaldson
  • H. Ikram
Case Report

DOI: 10.1007/BF02279894

Cite this article as:
Jardine, D.L., Melton, I.C., Bennett, S.I. et al. Clinical Autonomic Research (2000) 10: 69. doi:10.1007/BF02279894

Abstract

A 48-year-old woman presented with a history of progressive cough, dysphonia, dysphagia, and postural symptoms. Subsequent neurological investigations were consistent with a bilateral vagal mononeuropathy, and neurosarcoidosis was diagnosed after scalene node biopsy. Autonomic investigations including microneurography, neurohormones, and heart rate variability demonstrated arterial and cardiopulmonary baroreflex failure. In addition, parasympathetic control of heart rate was absent and consistent with a bilateral, nonselective lesion in the proximal vagus.

Key words

baroreceptorpostural hypotensionneurosarcoidvagus nervesympatheticnervous system

Copyright information

© Lippincott Williams & Wilkins 2000

Authors and Affiliations

  • D. L. Jardine
    • 1
  • I. C. Melton
    • 1
  • S. I. Bennett
    • 1
  • I. G. Crozier
    • 1
  • I. M. Donaldson
    • 1
  • H. Ikram
    • 1
  1. 1.Cardiology and Neurology DepartmentsChristchurch HospitalChristchurchNew Zealand
  2. 2.General Medicine DepartmentChristchurch HospitalChristchurchNew Zealand