Spinal MRI in progressive myeloneuropathy associated with vitamin E deficiency
- Cite this article as:
- Vorgerd, M., Tegenthoff, M., Malin, J.P. et al. Neuroradiology (1996) 38(Suppl 1): S111. doi:10.1007/BF02278134
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We describe a patient with a progressive neurological disorder consisting of ataxia, loss of proprioception and pyramidal tract dysfunction in his sixth decade. He had severe vitamin E deficiency due to fat malabsorption secondary to chronic inflammatory bowel disease. Sural nerve biopsy revealed a reduced number of myelinated fibres. MRI of the cervical spine showed high-signal lesions on T2-weighted images in the posterior columns, correlating well with the clinical findings.