Detection of antinuclear and antilaminin antibodies in autistic children who received thimerosal-containing vaccines
Received: 16 March 2004 Accepted: 05 April 2004 DOI:
Cite this article as: Singh, V.K. & Rivas, W.H. J Biomed Sci (2004) 11: 607. doi:10.1007/BF02256125 Abstract
Autism, a neurodevelopmental disorder, may involve autoimmune pathogenesis. Since mercury is potentially a risk factor for autoimmunity, we conducted a study of mercury-induced antinuclear and antilaminin antibodies in autistic and normal children who had been pre-administered with thimerosal-containing vaccines. Laboratory analysis by different immunoassays showed that the serum level of these two autoimmune markers did not significantly differ between autistic and normal children. This finding suggests that the mercury as in thimerosal-containing vaccines is likely not related to autoimmune phenomenon in autism.
Key Words Autism Autoimmunity Immunotoxicity Mercury Thimerosal References
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