, Volume 9, Issue 2, pp 100-111

HIV vaccine development in the nonhuman primate model of AIDS

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Development of a prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine is a leading priority in biomedical research. Much of this work has been done with the nonhuman primate model of AIDS. In a historical context, vaccine studies, which use this model, are summarized and discussed.