Psychopharmacology

, Volume 107, Issue 4, pp 503–510

Early dyskinesia — vulnerability

  • Jonathan O. Cole
  • George Gardos
  • Lenore A. Boling
  • David Marby
  • David Haskell
  • Patricia Moore
Original Investigations

DOI: 10.1007/BF02245263

Cite this article as:
Cole, J.O., Gardos, G., Boling, L.A. et al. Psychopharmacology (1992) 107: 503. doi:10.1007/BF02245263

Abstract

Relative vulnerability to dyskinesia in terms of exposure to antipsychotic drugs prior to onset of dyskinesia was studied in a sample of 100 psychiatric patients with dyskinesia onset generally within a year or less of the point of study entry. Unipolar and bipolar patients were more vulnerable to dyskinesia than other diagnostic groups. In the total sample, lithium exposure did not appear to delay development of dyskinesia. Longer exposure to antiparkinson drugs was associated with delayed onset of dyskinesia. Past exposure to electroconvulsive therapy was related to decreased vulnerability to dyskinesia.

Key words

Tardive dyskinesia Antipsychotic drugs Schizophrenia Depression Bipolar disorder 

Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Jonathan O. Cole
    • 1
  • George Gardos
    • 1
  • Lenore A. Boling
    • 1
  • David Marby
    • 1
  • David Haskell
    • 2
  • Patricia Moore
    • 2
  1. 1.McLean HospitalBelmontUSA
  2. 2.Boston VA Medical ClinicBostonUSA