, Volume 12, Issue 1, pp 60-64

Effect of glucose and glycine solution on the circulation of the isolated jejunal loop in the dog

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Isotonic glucose and glycine solution put into the isolated jejunal loop of the dog increased local blood flow and oxygen consumption. Similar but smaller increases were obtained with physiologic saline solution. An intraluminal pressure increase brought about by administering similar quantities of air caused no increase.

It is suggested that the observed changes in circulation are the consequence of an autoregulatory mechanism of the small intestine.