The American Journal of Digestive Diseases

, Volume 11, Issue 8, pp 587–593

Effect of antibiotic therapy on gluten-sensitive enteropathy

  • W. M. Roufail
  • Julian M. Ruffin

DOI: 10.1007/BF02233506

Cite this article as:
Roufail, W.M. & Ruffin, J.M. Digest Dis Sci (1966) 11: 587. doi:10.1007/BF02233506


In 2 cases of gluten-sensitive enteropathy, clinical recovery, partial in one and complete in the other, followed the administration of a gluten-free diet. When challenged with gluten both patients had a pronounced relapse. After the prolonged administration of tetracycline both patients have resumed a normal diet and show no effect when challenged with gluten. If these results can be confirmed in other patients, there must be a factor other than gluten in the so-called gluten-sensitive enteropathy.

Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1966

Authors and Affiliations

  • W. M. Roufail
    • 1
  • Julian M. Ruffin
    • 1
  1. 1.From the Department of MedicineDuke University Medical CenterDurham

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