, Volume 13, Issue 9, pp 783-791

Anabolic steroid therapy as an adjunct to diet in alcoholic hepatic steatosis

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Summary

Nine patients with severe alcoholic fatty livers were studied to evaluate the effects of aqueous testosterone and norethandrolone on the rate of fat removal from the liver. Serial liver biopsies showed that the addition of either of these anabolic steroids to a diet high in calories and protein reversed hepatic steatosis at a rate three to five times faster than that observed with diet alone. The relationship of this therapeutic effect to their actions on serum lipoproteins is discussed, but as yet no definite conclusions can be drawn.

Supported in part by Grant PHS AM5223 from the National Institutes of Health, U. S. Public Health Service.