Simulation of the electric-control activity of the stomach by an array of relaxation oscillators
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- Sarna, S.K., Daniel, E.E. & Kingma, Y.J. Digest Dis Sci (1972) 17: 299. doi:10.1007/BF02231729
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An array of bidirectionally coupled relaxation oscillators is proposed as a model of gastric electric-control activity. The characteristics of relaxation oscillators simulating control activity, such as intact and intrinsic frequency gradients and phase-lag patterns, were studied in anesthetized dogs. A marked intrinsic frequency gradient was found along the axis of the stomach, and a slight intrinsic frequency gradient around the circumference. The phase lag/cm decreased distally from the body of the stomach to the antrum. The model showed all these characteristics. Each oscillator in the array was represented by a system of two first-order nonlinear differential equations. The model was programmed on analog and hybrid computers.