Pharmaceutisch Weekblad

, Volume 10, Issue 6, pp 277–280

Screening of some essential oils for their activities on dermatophytes

Authors

  • A. M. Janssen
    • Division of Pharmacognosy, Center for Bio-Pharmaceutical SciencesLeiden University, Gorlaeus Laboratories
  • J. J. C. Scheffer
    • Division of Pharmacognosy, Center for Bio-Pharmaceutical SciencesLeiden University, Gorlaeus Laboratories
  • A. W. Parhan-Van Atten
    • Division of Pharmacognosy, Center for Bio-Pharmaceutical SciencesLeiden University, Gorlaeus Laboratories
  • A. Baerheim Svendsen
    • Division of Pharmacognosy, Center for Bio-Pharmaceutical SciencesLeiden University, Gorlaeus Laboratories
Original Articles

DOI: 10.1007/BF02219668

Cite this article as:
Janssen, A.M., Scheffer, J.J.C., Atten, A.W.P. et al. Pharmaceutisch Weekblad Scientific Edition (1988) 10: 277. doi:10.1007/BF02219668

Abstract

Fifty-three essential oils were tested against three frequently occurring dermatophytes (Epidermophyton floccosum, Trichophyton mentagrophytes var.interdigitale, T. rubrum) by means of an agar dilution technique. The oils were selected at random and not on the basis of a supposed activity. A number of oils showed interesting activities, expressed as maximum inhibitory dilution values, against the dermatophytes used. At the highest dilution tested (1:3,200, vol/vol), one out of six oils was active againstT. mentagrophytes var.interdigitale, and one out of three to four oils was active against the other dermatophytes.

Keywords

Agar dilution techniqueAntimycoticsDermatophytesDrug screeningEssential oilsStatistics
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Copyright information

© Bohn, Scheltema & Holkema 1988