Original Articles

European Archives of Psychiatry and Clinical Neuroscience

, Volume 243, Issue 6, pp 299-303

Neuroleptic malignant syndrome and catatonia

A report of three cases
  • Michele RajaAffiliated withOspedale “Santo Spirito”, Dipartimento di salute mentale USL RM11, Servizio Psichiatrico di Diagnosi e Cura
  • , Maria Concetta AltavistaAffiliated withOspedale “Santo Spirito”, Dipartimento di salute mentale USL RM11, Servizio Psichiatrico di Diagnosi e Cura
  • , Stefano CavallariAffiliated withOspedale “Santo Spirito”, Dipartimento di salute mentale USL RM11, Servizio Psichiatrico di Diagnosi e Cura
  • , Loredana LubichAffiliated withOspedale “Santo Spirito”, Dipartimento di salute mentale USL RM11, Servizio Psichiatrico di Diagnosi e Cura

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Summary

In a series of 1007 consecutively admitted patients, 3 cases of neuroleptic malignant syndrome (NMS) were identified (0.3%). All three patients were affected by mood disorders with congruent psychotic features, had shown catatonia just before the onset of NMS, and had been treated with low neuroleptic doses. All of them presented low serum iron levels. The relationship between NMS and catatonia and possible therapeutic decisions are discussed.

Key words

Neuroleptic malignant syndrome Catatonia